《四面體》發表了在有機化學領域及其在相關學科特別是生物有機化學中的應用中具有突出意義和時效性的實驗和理論研究成果。該雜志涵蓋的領域包括有機合成、有機反應、天然產物化學、反應機理研究和光譜學的各個方面。

Tetrahedron publishes experimental and theoretical research results of outstanding significance and timeliness in the field of organic chemistry and its application to related disciplines especially bio-organic chemistry. Areas covered by the journal include the many facets of organic synthesis, organic reactions, natural products chemistry, studies of reaction mechanism and various aspects of spectroscopy.