根據對一篇論文的潛在興趣、影響以及對臨床醫學和生物醫學社區的影響的編輯評估，該雜志發表生物醫學科學所有學科的原創研究。該雜志傾向于那些代表概念進步或理解發病機制和治療的分子基礎的原始方法的提交。

The journal publishes original research in all disciplines of biomedical science, according to editorial assessment of a paper's potential interest, impact, and implications for clinical medicine and the biomedical community. The journal favours submissions that represent a conceptual advance or an original approach to understanding the molecular basis of pathogenesis and therapy.