數學規劃出版涉及數學優化各個方面的原創文章;也就是說，所有直接或間接使用的關于優化多變量函數的問題，通常受一組約束。這包括理論和計算問題以及應用研究。包括線性、非線性、整數、圓錐、隨機和組合優化等標準主題，從數學規劃的角度闡述和應用數學規劃模型、凸、非光滑和變分分析、多面體理論、變分不等式、控制和博弈論。編輯委員會對數學編程的新應用和與工程、經濟學和計算機科學的接口特別感興趣。一般來說，主要涉及計算問題(如實現和測試)的文章應該提交給數學編程計算。數學規劃由兩個系列組成。A系列出版關于計算實驗、新的或創新的實際應用以及處理上述問題的簡短通信的原創研究文章、展覽和調查報告。B系列的每個問題都集中在數學編程社區當前感興趣的一個主題上。每一期B輯都有一個或多個客座編輯，他們不必是編委會成員。一個問題可能是一個原始文章的集合，一個單一的研究專著或一個會議的論文選擇。

Mathematical Programming publishes original articles dealing with every aspect of mathematical optimization; that is, everything of direct or indirect use concerning the problem of optimizing a function of many variables, often subject to a set of constraints. This involves theoretical and computational issues as well as application studies. Included, along with the standard topics of linear, nonlinear, integer, conic, stochastic and combinatorial optimization, are techniques for formulating and applying mathematical programming models, convex, nonsmooth and variational analysis, the theory of polyhedra, variational inequalities, and control and game theory viewed from the perspective of mathematical programming. The editorial boards are particularly interested in novel applications of mathematical programming and interfaces with engineering, economics, and computer science. Articles primarily concerned with computational issues such as implementation and testing should in general be submitted to Mathematical Programming Computation.Mathematical Programming consists of two series. Series A publishes original research articles, expositions and surveys, and reports on computational experimentation and new or innovative practical applications as well as short communications dealing with the above. Issues of Series B each focus on a single subject of current interest to the mathematical programming community. Each issue of Series B has one or more guest editors, who need not be members of the editorial board. An issue may be a collection of original articles, a single research monograph or a selection of papers from a conference.