分子生物學雜志在分子生物學的各個領域提供了高質量、全面和廣泛的報道。該雜志出版原始科學研究論文，提供機械和功能的見解，并報告了該領域的重大進展。該雜志鼓勵提交多學科研究，使用互補的實驗和計算方法來解決具有挑戰性的生物學問題。研究范圍包括但不限于:生物分子相互作用，信號網絡，系統生物學細胞周期，細胞生長，細胞分化細胞死亡,自噬細胞信號與調控化學生物學計算生物學，結合實驗研究DNA復制、修復和重組干細胞的發展，再生生物學，機械和功能研究表觀遺傳學，染色質結構和功能基因表達膜過程，細胞表面蛋白和細胞間的相互作用方法的進步，包括實驗和理論，包括數據庫微生物學、病毒學以及與宿主或環境的相互作用微生物群的機制和功能研究核組織轉錄后修飾、蛋白質組學具有重要生物學意義的大分子及其配合物的加工和功能疾病的分子基礎RNA處理，非編碼RNA的結構和功能，轉錄分類，時空組織，人口販賣結構生物學合成生物學翻譯，蛋白質折疊，伴侶，蛋白質降解和質量控制

The Journal of Molecular Biology provides high quality, comprehensive and broad coverage in all areas of molecular biology. The journal publishes original scientific research papers that provide mechanistic and functional insights and report a significant advance to the field. The journal encourages the submission of multidisciplinary studies that use complementary experimental and computational approaches to address challenging biological questions.Research areas include but are not limited to:Biomolecular interactions, signaling networks, systems biologyCell cycle, cell growth, cell differentiationCell death, autophagyCell signaling and regulationChemical biologyComputational biology, in combination with experimental studiesDNA replication, repair, and recombinationDevelopment, regenerative biology, mechanistic and functional studies of stem cellsEpigenetics, chromatin structure and functionGene expressionMembrane processes, cell surface proteins and cell-cell interactionsMethodological advances, both experimental and theoretical, including databasesMicrobiology, virology, and interactions with the host or environmentMicrobiota mechanistic and functional studiesNuclear organizationPost-translational modifications, proteomicsProcessing and function of biologically important macromolecules and complexesMolecular basis of diseaseRNA processing, structure and functions of non-coding RNAs, transcriptionSorting, spatiotemporal organization, traffickingStructural biologySynthetic biologyTranslation, protein folding, chaperones, protein degradation and quality control