基因組生物學和進化(GBE)發表領先的原始研究在進化生物學和基因組之間的接口。考慮發表的論文報告了新的進化發現，涉及自然基因組多樣性、群體基因組學、基因組的結構、功能、組織和表達、比較基因組學、蛋白質組學和環境基因組相互作用。從計算生物學、結構生物學、發育生物學和細胞生物學領域的主要進化見解，以及基因組進化領域的理論進展也被考慮在內。GBE的范圍包括在所有分類水平上的全基因組的進化研究，以及在種群內或跨域內的所有生命形式。其目的是進一步了解基因組的進化背景，并進一步從基因組的角度理解進化。GBE為分子生物學和進化學會(SMBE)所有。受該領域持續增長的推動，測繪處于2007年進行了一項基層調查，以調查該領域對新出版機構的需求。這項調查引起了SMBE成員以及基因組學和分子進化領域其他科學家的強烈反應。那次調查的主要發現是，該領域想要一本專門研究基因組進化和比較基因組領域的在線雜志，并且是在開放獲取模式下出版的。SMBE的反應是推出GBE，以滿足該領域的這些需求。SMBE會議每年吸引約800名與會者。作為基因組技術快速發展的反映，在每次SMBE會議上，大約有一半的科學是關于基因組的。在SMBE收集的進化專業知識的幫助下，GBE的定位和設計旨在為不斷增長的進化基因組學領域的論文設定最高標準。

Genome Biology and Evolution (GBE) publishes leading original research at the interface between evolutionary biology and genomics. Papers considered for publication report novel evolutionary findings that concern natural genome diversity, population genomics, the structure, function, organisation and expression of genomes, comparative genomics, proteomics, and environmental genomic interactions. Major evolutionary insights from the fields of computational biology, structural biology, developmental biology, and cell biology are also considered, as are theoretical advances in the field of genome evolution. GBE’s scope embraces genome-wide evolutionary investigations at all taxonomic levels and for all forms of life — within populations or across domains. Its aims are to further the understanding of genomes in their evolutionary context and further the understanding of evolution from a genome-wide perspective.GBE is owned by the Society for Molecular Biology and Evolution (SMBE). Motivated by the continued growth of the field, SMBE conducted a grass-roots survey in 2007 to investigate the needs of the field regarding new publication outlets. The survey elicited a resounding response from members of SMBE and other scientists in the fields of genomics and molecular evolution. The key findings from that survey were that the field wanted an online only journal that was devoted specifically to the areas of genome evolution and comparative genomics and that was published under an Open Access model. The response of SMBE was to launch GBE in order to serve those needs of the field. The SMBE meeting attracts about 800 participants each year. As a reflection of the rapid growth of genomic technologies, about half of the science presented at each SMBE meeting is about genomics. With the help of the evolutionary expertise that is gathered in SMBE, GBE is positioned and designed to set the highest standards for papers in the growing field of evolutionary genomics.