BBA一般受試者接受提交原始的、假設驅動的研究或評論，這些研究或評論涉及生物化學和生物物理領域的受試者，這些學科被認為對廣泛的受眾具有普遍興趣。特別鼓勵采用跨學科方法的手稿。首選主題包括醫學上重要的生物化學/生物物理研究和新興領域，如納米生物學（納米粒子、納米毒理學、納米醫學）、系統生物學（基因組學、蛋白質組學、脂質組學、糖組學、基于實驗方法的生物信息學）、化學生物學（化學化合物、藥物機制、合成新的化合物，點擊化學），結構生物學（結晶學，核磁共振，多聚蛋白質，蛋白質動力學），新的復合物（純天然化合物，合成化合物，蛋白質復合物，核酸衍生物），細胞信號傳導（受體信號，蛋白質磷酸化級聯，磷酸酶，二級信使，轉錄調節因子糖化、基因表達）、糖生物學（糖代謝產物和代謝、糖基化蛋白、膜蛋白、糖基化、糖代謝）、氧化還原生物學（氧化還原開關、谷胱甘肽和硫氧還蛋白系統、氧和氮自由基物種、超氧化物、過氧化氫、羥基自由基、一氧化氮、過氧化物、缺氧、氧化還原調節轉錄因子）、神經生物學（神經元生長因子和神經信號傳導、膠質細胞、自主神經和中樞神經系統）、干細胞（分化、干細胞分離和培養、生長因子）、具有生化重要性和一般意義的化合物的成像方法學和機械特性（藥物先導），有毒物質，營養物質，代謝物）。作者必須在提交時提供一句話，說明原稿中描述的工作對廣大讀者具有普遍意義和興趣的原因。聲稱新穎性還不夠。作者聲明將作為審查過程中的一個輔助，并將包括在接受的論文的最終版本中，以確定BBA一般主題的讀者的方向。

BBA General Subjects accepts for submission either original, hypothesis-driven studies or reviews covering subjects in biochemistry and biophysics that are considered to have general interest for a wide audience. Manuscripts with interdisciplinary approaches are especially encouraged.Preferred topics include medically important biochemistry/biophysics research and emerging areas such as nanobiology (nanoparticles, nanotoxicology, nanomedicine), systems biology (genomics, proteomics, lipidomics, glycomics, bioinformatics based on experimental approaches), chemical biology (chemical compounds, drug mechanisms, synthesis of novel compounds, click chemistry), structural biology (crystallography, NMR, multimeric proteins, protein dynamics), novel complexes (pure natural compounds, synthetic compounds, protein complexes, nucleic acid derivatives), cellular signaling (receptor signaling, protein phosphorylation cascades, phosphatases, secondary messengers, transcription regulation, gene expression), glycobiology (sugar metabolites and metabolism, glycosylated proteins, membrane protein, glycosylation, glycomics), redox biology (redox switches, glutathione and thioredoxin systems, oxygen and nitrogen radical species, superoxide, hydrogen peroxide, hydroxyl radical, nitric oxide, peroxides, hypoxia, redox regulation of transcription factors), neurobiology (neuronal growth factors and nerve signaling, glial cells, autonomic and central nervous systems), stem cells (differentiation, stem cell isolation and cultivation, growth factors), imaging methodologies and mechanistic characterization of compounds having biochemical importance and general interest (drug leads, toxicants, nutrients, metabolites).Authors must provide a sentence at submission stating the reason that the work described in the manuscript has general significance and interest to a wide audience. Claims of novelty do not suffice. The author statement will be used as an aid in the reviewing process and will be included in the final version of the accepted paper to orient readers of BBA General Subjects.